Irregular accumulating of melanin within the epidermis can cause uneven tones
and skin pigmentation. Melanin is produced by melanocyte, a pigment cell within epidermis. Within melanocytes,
an enzyme called tyrosinase utilizes tyrosine to generate pigment melanin. To evaluate the effect of Brightum***
on melanin production, an in-vitro assay was generated to mimic the process which tyrosinase utilizes tyrosine to
plus Brightum could be added. The results were obtained by quantifying melanin levels.
Brightum significantly reduce
The results indicate that Brightum*** significantly reduces melanin
production. These data also suggest the potential role of Brightum in
mediating melanocyte to produce less pigment melanin.
To further evaluate the effect of Brightum*** on human skin tones, a
clinical study of 24 volunteers were conducted. Cream containing with/without
Brightum was applied twice a day for 28 days. At the beginning and end of this study,
the color of skin was measured by a chromameter. The results were analyzed by using skin color topology.
Data was summarized by using typology angles generated from
Brightum enhances skin fibroblast
The results indicate that Brightum*** significantly increases skin clarity
and decreases skin pigmentation.